Peripheral t-cell lymphomas: progress and challenges
نویسنده
چکیده
Peripheral T-cell lymphomas (PTCLs) represent a complex group of diseases that remain a management challenge today. Although CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone) is considered the standard therapy, outcomes are disappointing and relapses are frequent. Therapeutic progress has lagged behind that for the more common and aggressive B-cell lymphomas. With disease rarity, studies are small and often retrospective in nature. A number of novel agents are now being tested exclusively in PTCLs, some with promising activity that are moving into the clinical care setting.
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